Title: IN-VITRO RESPONSE OF FIBROBLASTS TO POLY-L-LACTIDE COMPOSITE MATERIALS CONTAINING BOVINE BONE
Page Range: p.531-536
Author(s): Zeqiang He; Lizhi Xiong
File size: 328K
Download the pdf (subscribers only)
Buy the pdf (non-subscribers)
Journal: Polymers and Polymer Composites
Issue Year: ppc
Volume: 20
Issue No: No.6
Abstract
This study aimed to investigate the interaction between fibroblastic cells and poly-L-lactide (PLLA) composite film containing bovine bone. The effects of PLLA/bovine bone on cell cytotoxicity, attachment, proliferation and differentiation of fibroblasts in-vitro were investigated. The results of cytotoxicity tests showed that cells cultured in extracts of PLLA/bovine bone and on the surface of composites showed normal growth and proliferation, and mineralisation nodules were observed for fibroblasts cultured in PLLA/bovine bone extract at day 7 by using von Kossa staining and tetracycline staining. Compared with pure PLLA materials, bovine bone in the PLLA composites facilitated both adhesion and proliferation of rat fibroblasts on the PLLA/bovine bone composite film. In conclusion, these results suggest that the introduction of bovine bone may improve the cell response involved in the osteogenesis and thus may be beneficial to further modify poly-L-lactide as a better bone repairing material. 15 Refs.
Related reading
More journal reading and science coverage connected to this topic.
Direct and flexural shear strength of composite beam with perforbond rib
Title: Direct and flexural shear strength of composite beam with perforbond rib Page Range: p.9-18 Author(s): Dooyong Cho; Jinwoong Choi; Hoseong Jeong File size:…
A study of cutting temperatures in turning carbon-fiber-reinforced-plastic (CRFP) composites with nose radius worn tools
Title: A study of cutting temperatures in turning carbon-fiber-reinforced-plastic (CRFP) composites with nose radius worn tools Page Range: p.19-26 Author(s): Chung-Shin Chang File size:…
Curing residual strain monitoring of carbon fiber reinforced polymer composite using notched long-period fiber grating
Title: Curing residual strain monitoring of carbon fiber reinforced polymer composite using notched long-period fiber grating Page Range: p.27-34 Author(s): Ke-Ping Ma; Chao-Wei Wu;…